Gold(I)-catalysed [1,3] O→C rearrangement of allenyl ethers.
نویسندگان
چکیده
A simple and rapid access to the α-substituted acryl aldehydes has been provided by developing a gold-catalysed [1,3] rearrangement of the allenyl ethers importantly with a record turnover frequency of 4600 h(-1) (at 0.05 mol% of the catalyst concentration) in homogeneous gold(I) catalysis.
منابع مشابه
Gold(I)-catalyzed Claisen rearrangement of allenyl vinyl ethers; synthesis of substituted 1,3-dienes.
Synthesis of substituted 1,3-dienes was achieved via gold(I)-catalyzed Claisen rearrangement of allenyl vinyl ethers. The N-heterocyclic carbene gold chloride catalyst (IPrAuCl) was superior in terms of activity and selectivity and afforded the 3,3-product in excellent yields. A proposed cation-π inter-action played a significant role in affecting the reaction rate.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 17 شماره
صفحات -
تاریخ انتشار 2014